Research conclusions: Facing the serious safety production situation，the construction enterprise should adhere to the outlooks of the scientific development and safety development，set up the concept of " zero accident" ，that is to say every safety accident can be prevented． In addition，the implement capacity of the enterprise should be strengthened，the organization security system for the safety production should be built and improved，the rules and systems for the safety production should be worked out， the check and control of the hidden danger of safety production should be strengthened，the education and training for the safety production should be improved，the supporting role of science and technology should be played in the safety production and the key and important links should be strictly controlled． At the same time，it is necessary for the country and the industry to improve the law and rule sytems，normalize the admittanceof construction market，the bidding flow and the working out financial estimate，optimize the project design，scientifically decide the construction period，normalize the construction supervision，reduces the local interference and correctly guide the supervision of the public opinion． The measures mentioned above are crucial to the safety production and scientific， safe and healthy development of the large － sized construction enterprise．