Research conclusions: This paper systemically summarizes the principle of the “route selection combining geology and environmental geology for railway engineering in high-intensity earthquake zone.By the means of remote sensing interpretation， geological mapping，geophysical prospecting(by electricity，seismic waves，or magnetotellurics etc.)， drilling exploration，hole testing，in-situ testing，indoor tests and other comprehensive prospecting technique，as well as seismic safety evaluation(including active fault identification)，environmental effect appraisal，this complete system is constituted，which has an important value to promote. An optimal route scheme is selected through overall comparison among three schemes from the aspects of seismic geological conditions and environmental sensitive area，and then verified by engineering construction and practical operation to be scientific and reasonable，which not only protects the ecological environment to a maximum extent，but also includes the route into a“safe island”.With outstanding economic，social and environmental benefits，it is the “Example of Route Selection Combining accumulating experience for railway route selection praised by experts from the Ministry of Environmental Protection as Engineering Geology and Environmental Geology Organically” ， in similar region.