Research conclusions: In the paper, the study shows in the river reach with above-mentioned characteristics of river reach the design of bridge is generally controlled by multiple factors. Therefore, the comparison can be made on multiple schemes in combination with practical circumstances. It is thought that the abnormal-shape prestressed concrete continuous beam bridge of which side-middle span ratio is smaller obviously than normal that is sometime a better selection of bridge type. For this bridge type, it is key to take measures for preventing bridge side bearing from occurrence of tension. It is suggested to take such a counter weight measure that the side span is solid section and widened transversely and thickened vetically, if necessary, the concrete blocks can be set at the bottom of beam for counter weight.