Research conclusions：With the renewal of the concept on civil engineering design, the technician should pay more attention to the bridge structure design for disaster prevention and reduction of bridge. It is necessary to make the ductility design for earthquake resistance to complicated bridges. Through seismic analysis of large span continuous rigid frame bridge in intense earthquake area under rarely strong earthquake, this paper offers an effective ductility design method. Namely, using non-linear temporal analysis method gains the force and displacement of the piers, and comparing the response results with the yield-resistant capacity of each pier gained through Pushover analysis determines whether the bridge has enough ductile earthquake-resistant capacity or not.