The Beijing-Shanghai high-speed railway which will be built in the near future is an important railway. During the site investigation of the Nanjing Yangtze River Bridge of this railway,the water area shallow seismic profile method and the land shallow seismic re?flection method are mainly employed. Based on the bridge comprehensive investigation exam?ple, the geophysical ex； oration,the drill method and their relationships are analysed in this paper.