Abstract ： Research purposes ： With the development of the train speed and the high speed and heavy haul railway， train bridge interaction， bridge seismic and other bridge dynamic structure is becoming increasingly prominent， the Chongqing - Guizhou railway Chaomen Wujiang bridge (92 + 168 +92) m Prestressd Concrete Continuous Rigid Frame Bridge as the engineering background，the dynamic problems including self vibration characteristics，seismic response spectrum，the vehicle bridge coupling are analyzed，the safety and comfort of the bridge are analyzed and evaluated， which provide the basis for the design of the dynamic structure of the bridg. Research conclusion ：( 1) In the calculation and analysis of tiie structure of tiie structure，the effect of pile soil and the side pier has some effect on the overall stiffness of the stricture. (2) When the main pier continuous rigid frame is high， the lateral stiffener is difficult to meet，the main pairs with two variable slope can be considered，which can significantly improve the lateral stiffness of the stricture，optimize the quality of distribution，and make the stricture lateral stiffness meet the requirements of the railway. ( 3 ) High pier and long - span strictures should be analysis of coupling vibration of vehicle bridge， considering interaction of train track structure， ensure vehicle running safety and comfort. ( 4 ) The research results can provide guidance and reference for the dynamic analysis of similar high pier and long span railway continuous rigid frame bridge.